Effectiveness of Adding Subcutaneous Long-Acting Detemir to Insulin Drip Therapy Compared With Standard Insulin Drip Therapy This study is not yet open for participant recruitment. Purpose The investigators anticipate that the use of Detemir will decrease the duration of an insulin drip, the dose of short-acting insulin in the drip, hospital and ICU (intensive...
Epigenetic Regulation of BDNF in Major Depression This study is currently recruiting participants. Purpose The investigators will (1) detect the associations between BDNF DNA methylation, histone modification, depressive symptoms, suicidal behavior and antidepressant responses in major depressive patients (2) check the correlation between blood BDNF protein and RNA and BDNF rs6265 gene (3) discuss...
Efficacy of Oxygen Therapy Delivered by Systems Using Oxygen-Saving Valves in Patients With Chronic Obstructive Pulmonary Disease (COPD) This study is currently recruiting participants. The purpose of this study is to compare the efficacy of oxygen therapy delivered by systems using oxygen-saving valves or not (continuous oxygen). We aim to determine if systems using...
A Trial Investigating the Exposure of NN5401 in Young Adults and Elderly Subjects With Type 1 Diabetes This study is currently recruiting participants. This trial is conducted in Europe. The aim of this trial is to investigate the exposure of NN5401 in young adults and elderly subjects with type 1 diabetes mellitus. ...
Evaluation of PillCam® Colon 2 Capsule Endoscopy Regimen This study is currently recruiting participants. The purpose of the study is to test the effect of a bowel preparation and boosts regimen on PillCam® procedure, colon cleanliness and capsule excretion time. Phase Condition: Colonoscopy Endoscopy Intervention : Other: PillCam® COLON 2 procedure using...
Electronic Compliance Monitoring in Opioid Substitution Treatment (EHSO) This study is not yet open for participant recruitment. The purpose of this study is to improve unsupervised dosing of opioid substitution medications. The aim of the study is to examine whether electronic compliance monitoring provides some advantages to patients`treatment and what kind of patients especially...
Obesity is an established risk factor for development and progression of kidney disease. Intentional weight loss in people without kidney disease results in an improvement in diabetes, blood pressure, cholesterol, cardiovascular disease and overall death rates. We do not know whether this holds true in patients with chronic kidney disease. In the proposed pilot...
A Study to Assess the Efficacy and Safety of TC-5214 as an Adjunct Therapy in Patients With Major Depressive Disorder soon to be recruiting. The purpose of this study is to determine if TC-5214 or placebo (a tablet that looks like medicine tablet or capsule, but contains no active medicine) is safe and effective...