R5 Integrase Study in HIV-1 Naive Patients This study is currently recruiting participants. Purpose This is a pilot, open-label study of raltegravir and maraviroc in combination for the treatment of antiretroviral naïve patients. The study will enroll 10 antiretroviral naïve patients with CD4 counts > 500 and viral loads > 5,000. The subjects...
In the United States, someone becomes infected with HIV every nine and a half minutes. More than 20 percent of the estimated 1.1 million Americans living with HIV infection do not know they are infected. People at high risk for HIV infection include substance abusers and their sexual partners, gay and bisexual men, female...
Over the past several decades, scientists and researchers have discovered a lot about the human immunodeficiency virus (HIV) and the disease it is related to, acquired immunodeficiency syndrome (AIDS). But still, more research and information is needed to help the millions of people whose health continues to be threatened by the global HIV/AIDS pandemic....
1 in 4 deaths worldwide are caused by infectious diseases, including about two-thirds of all deaths among children younger than age 5. Scientists have worked to combat infectious diseases by helping to develop new therapies, vaccines, diagnostic tests, and other technologies. Vaccines can now protect children against once-common infections, like chicken pox, measles, mumps...
An immunotoxin is a human-made protein that consists of a targeting portion linked to a toxin. When the protein binds to that cell, it is taken in through endocytosis, and the toxin kills the cell. They are used for the treatment of some kinds of cancer and a few viral infections. The immunotoxin chimeric...