AAV vectors offer unique advantages in gene therapy applications. Studies have shown that these replication deficient parvovirus vectors can deliver DNA to specific tissues and confer long-term transgene expression in a variety of systems. Although many studies have looked at the tissue-specific expression elicited by each of the AAV serotypes, a true understanding of...
Scientists have found that individuals who carry a mutation in a gene called BAP1 are susceptible to developing two forms of cancer — mesothelioma, and melanoma of the eye. Additionally, when these individuals are exposed to asbestos or similar mineral fibers, their risk of developing mesothelioma, an aggressive cancer of the lining of the...
Members of the local media are invited to attend a press availability followed by a roundtable discussion on the multiple benefits of federally-funded research. Join local researchers as they discuss how funding from federal agencies is allowing them to do cutting-edge science and medical research that is benefiting the citizens of North Carolina and...
Regular exercise could help prevent brain damage associated with neurodegenerative diseases like Alzheimer’s, according to research published this month in Elsevier’s journal Brain, Behavior, and Immunity.
New findings in mice suggest that the timing when the neurotransmitter acetylcholine is released in the brain’s hippocampus may play a key role in regulating the strength of nerve cell connections, called synapses. Understanding the complex nature of neuronal signaling at synapses could lead to better understanding of learning and memory, and novel treatments...
An NIH-funded network of researchers will evaluate potential harmful effects of the Deepwater Horizon disaster on reproduction and birth outcomes, the cardiorespiratory system, and behavior and mental health. The network of community and university partnerships, under the leadership of NIH’s National Institute of Environmental Health Sciences (NIEHS), will conduct research to evaluate the level...