The National Institutes of Health will award $9.4 million over three years to support four research projects in regulatory science. This research is conducted in partnership with the U.S. Food and Drug Administration, which will contribute approximately $950,000. These projects will better inform scientists and regulatory reviewers alike about medical product safety, and improve...
Arthroscopic Rotator Cuff Repair With Multimodal Analgesia(MMA) This study is currently recruiting participants. Purpose The purpose of this study is to compare the efficacy of periarticular injections consisting of ropivacaine, morphine, epinephrine, cefotetan, and hyaluronic acid with the efficacy of periarticular injections consisting of the same amount of placebo(isotonic saline) during arthroscopic rotator...
The Effects of Atorvastatin on the Nitrogen Oxide-system in Patients With Type 2 Diabetes and Nephropathy (STAD) This study is currently recruiting participants. Purpose It has been documented that statin reduce mortality and morbidity in patients with cardiovascular disease. This effect can partly be related to a reduction in cholesterol levels in blood....
Paracervical Block Before IUD Insertion This study is currently recruiting participants Purpose The purpose of this study is to evaluate if a paracervical block containing 1% lidocaine administered prior to IUD insertion reduces insertion pain. The hypothesis is that women receiving paracervical analgesia will experience less pain during IUD insertion than those who...
Pilot Study of Bisphosphonate Therapy (Zoledronic Acid) in Patients With Malignant Mesothelioma (UAB 0901) This study is currently recruiting participants. Purpose The primary objective of this trial is to determine the response rate of single agent zoledronic acid using a composite of criteria including the EORTC modified RECIST criteria and the EORTC tumor...
Endometriosis What is endometriosis? Endometriosis is one of the most common gynecological diseases, affecting more than 5.5 million women in North America. An estimated 2 percent to 10 percent of women of reproductive age have endometriosis. Endometriosis occurs when tissues that usually grow inside uterus instead grow on the outside. These tissues often grow...
Ovarian cancer is the fifth deadliest cancer among women nationwide. The subtype known as ovarian clear cell carcinoma is poorly understood and can be especially resistant to standard therapy. To learn more about the genetic origins of ovarian clear cell carcinoma, 2 independent teams of scientists used different techniques to examine the exons, or...
U.S. Commerce Secretary Gary Locke today announced the winners of the i6 Challenge, a new $12 million innovation competition led by the U.S. Department of Commerce’s Economic Development Administration (EDA), in partnership with the National Institutes of Health (NIH) and the National Science Foundation (NSF). Locke made the announcement during his keynote remarks at...
The National Institute of Environmental Health Sciences (NIEHS) is awarding $36 million in grants to 20 organizations that develop safety and health training for workers involved in hazardous waste operations and transportation, environmental restoration of contaminated facilities, and chemical emergency response. These training programs can receive annual funding for up to five years. “For...